Centrale Lille Course Catalogue

Toxicology

Course label : Toxicology
Teaching departement : CMA /
Teaching manager : Mister OLIVIER GABUT
Education language :
Potential ects : 0
Results grid :
Code and label (hp) : ENSCL_CI_M7_2_4_2 - Toxicologie

Education team

Teachers : Mister OLIVIER GABUT
External contributors (business, research, secondary education): various temporary teachers

Summary

Course unit 7.6 ᅵ Toxicology seeks to raise awareness among engineering students about toxicology, i.e. the study of the interaction between a toxic agent, of natural or anthropogenic origin, and a biological target. In order to provide engineering students with the general and fundamental concepts needed to understand toxicology within the framework of their studies, it endeavours to present the different contamination pathways of toxic agents and to explain their pathways in the body, then examines the assessment of toxicity in its various forms by integrating the physico-chemical and biological properties of toxic agents. It then covers the assessment of hazards and risks in an environmental and/or professional situation. The toxicology portion of course unit 7.6 will seek, in particular, to provide engineering students with the following knowledge and skills: Knowledge: - Health-environment relationship - Typology and sources of pollutants of natural and/or anthropogenic origin - Dose-response relationships - Structure-activity (quantitative) relationship - Toxicokinetics - absorption, distribution, metabolism, elimination - Toxicodynamics - action mechanisms of toxins - Exposure assessment methods - expology applied in an environmental and/or professional setting - Assessment of exposure to typical environmental and/or industrial pollutants (e.g. VOCs, PAHs, metals) Skills: - Be able to identify the sources and typology of pollutants in environmental and/or professional situations - Be able to analyse the behaviour of toxic agents in an environmental and/or professional setting according to their physico-chemical properties and emission sources/conditions - Be able to define the dose-response relationship of a toxic agent - Be able to understand the toxicokinetics of a toxic agent - Be able to understand the critical effect of a toxic agent and associated pathologies - Be able to assess exposure to a toxic agent in an environmental and/or professional setting - Be able to implement general and specific prevention measures

Educational goals

By referring to the knowledge and skills acquired during this course unit, be familiar with and know how to apply the procedure for assessing hazards and exposure on site in environmental and/or professional situations.

Sustainable development goals

Knowledge control procedures

Continuous Assessment
Comments: A final exam in the form of a case study with a series of questions assesses the theoretical knowledge and practical skills acquired by the students.

Online resources

"Casarett and Doull's Toxicology: the basic science of poisons". Klaassen, Curtis D, 8th ed. New York: McGraw-Hill Education, 2013. "Toxicologie : fondamentaux et fiches" (Toxicology: fundamentals and fact sheets). Xavier Coumoul DUNOD ISBN 13: 9782100761739 "Toxicologie industrielle et intoxications professionnelles" (Industrial toxicology and occupational poisoning). Robert Lawerys and Dominique Lison. MASSON ISBN: 9782294014185

Pedagogy

Module' curriculum: - Introduction to toxicology and health risk assessment - Toxicokinetics - absorption, distribution, metabolism, elimination - Toxicodynamics - action mechanisms of toxins - Method for assessing exposure in an environmental and/or professional setting - Examples of application (e.g., VOCs, PAHs, metals) Teaching tools: - Course materials, publications and reference works, websites - Theoretical courses and applications to exposure situations in an environmental and/or professional setting (case study) - Language: French

Sequencing / learning methods

Number of hours - Lectures : 17
Number of hours - Tutorial : 0
Number of hours - Practical work : 0
Number of hours - Seminar : 0
Number of hours - Half-group seminar : 0
Number of student hours in TEA (Autonomous learning) : 0
Number of student hours in TNE (Non-supervised activities) : 0
Number of hours in CB (Fixed exams) : 0
Number of student hours in PER (Personal work) : 0
Number of hours - Projects : 0

Prerequisites

Knowledge and skills acquired in Life and Earth Sciences in upper secondary education.

Maximum number of registrants

Remarks

A distance-learning refresher course is possible for students who no longer have the required level in biology.